print_label | resize_label

Dosing and Administration

Select a category or scroll to learn more.


BYETTA offers 1-step titration

  • Initiate BYETTA (exenatide) injection at 5 mcg BID to reduce the incidence and severity of gastrointestinal side effects.
  • Based on clinical response, increase to 10 mcg BID after 1 month of therapy and maintain thereafter.

    – No additional dose adjustments are required around meals or exercise.

  • Administer BYETTA subcutaneously at any time within the 60 minutes before the morning and evening meals (or the 2 main meals of the day, at least 6 hours or more apart). Do not administer after a meal.
  • Do not mix BYETTA with insulin. Do not transfer BYETTA from the pen to a syringe or a vial.
  • When BYETTA is used in combination with insulin, the dose of insulin should be evaluated. In patients at increased risk of hypoglycemia, consider reducing the dose of insulin.
BYETTA Pen dosing
BYETTA Pen dosing

Prior to first use, the BYETTA Pen should be stored in the original carton in a refrigerator at 36°F to 46°F (2°C to 8°C). After the BYETTA Pen is first used, it can be stored at room temperature not to exceed 77°F (25°C). Do not freeze.

BYETTA By Your Side®

Help your patients get started with and stay on BYETTA.

BYETTA PATIENT SAVINGS


How to prescribe BYETTA

Based on clinical response, the dose of BYETTA can be increased to 10 mcg twice daily after 1 month of therapy. Initiation with 5 mcg reduces the incidence and severity of gastrointestinal side effects.

BYETTA Pen prescription example

Note: A separate prescription may be required for needles.


Instructions for use

Review step-by-step instructions on how to use the BYETTA Pen with your patients.

View User Manual  

BYETTA By Your Side®

Help your patients get started with and stay on BYETTA.

BYETTA PATIENT SAVINGS